ULTRACENTRIFUGAL STUDIES OF MAJOR NON-LIPIDE ELECTROPHORETIC COMPONENTS OF NORMAL HUMAN SERUM

Ultracentrifugal studies of major non-lipide electrophoretic components of normal human serum.

In the ultracentrifuge, normal human serum shows, in addition to the lipoproteins, three distinct components with sedimentation rates of approximately 4, 7, and 19 Svedberg units (1, 2). Other materials known to be present are obscured by the high concentrations of these major substances and the high diffusion spreading of the boundaries. For example, Edsall (3) has reported a number of additio...

Ultracentrifugal studies of lipoproteins of human serum.

In spite of several extensive ultracentrifugal studies of human sera by Mutaenbecher, McFarlane, and Pedersen, the interpretation of the patterns observed has remained in doubt. Specifically, the greatest difficulties encountered by previous workers have arisen in their efforts to study undiluted human sera. McFarlane (1) referred to marked distortions in the pattern observed with undiluted hum...

Electrophoretic and ultracentrifugal analysis of serum lipoproteins of normal, nephrotic and hypertensive persons.

Electrophoretic studies on human serum.

Archibald, R. M. (1944). J. biol. Chem. 154, 643. Coulson, R. A., Ellinger, P. & Holden, M. (1944). Biochem. J. 38, 150. Ellinger, P. (1946a). Biochem. J. 40, xxxi. Ellinger, P. (1946b). Biochem. J. 40, xxxii. Ellinger, P. & Coulson, R. A. (1944). Biochem. J. 38, 265. Ellinger, P., Fraenkel, G. & Abdel Kader, M. M. (1947). Biochem. J. 41, 559. Johnson, B. C. (1945). J. biol. Chem. 159, 227. Kon...

The ultracentrifugal analysis of normal and pathological serum fractions.

IN this paper, 'which is the concluding one of the series, we are concerned with the fractionation, by means of a neutral electrolyte and electrodialysis, of a few sera which have already been investigated in the ultracentrifuge [McFarlane, 1935, 1, 2, 3]. The particular objects in view have been (1) to investigate the composition of the globulin fractions obtained by a single precipitation wit...